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Topic: Blood |
Rationale: Students will discover contributions made to the study of blood throughout history; noting how these advanced scientific knowledge. Students will examine and identify parts of the blood, antigens, antibodies, and blood types, and also infer how genes and chromosomes determine blood types.
Keywords: agglutination, antibody, antigen, blood group, blood innovator, blood transfusion, blood type, blood, chromosome, gene, genome, history, inherit, karyotype, nucleus, punnett square, red blood cell, research, scientific knowledge, scientist, timeline, trait, erythrocyte, white blood cell, leukocyte, platelet, thrombocyte, granulocyte, lymphocyte, T cell, B lymphocyte, monocyte, macrophage, neutrophil, eosinophil, basophil, hemoglobin
Lessons & Activities | Objectives | Evaluation | Funding
Unit Objectives
Students will be able to:
Examine the different parts of blood
Identify the parts of blood and construct a model of human blood
Differentiate between non-specific and specific immune responses
Model the disease fighting process of some major immune cells in the body
Explain that structure is related to function
Construct antigen/antibody complexes and understand their basic role in human immune responses
Model the interaction of the immune subsystems when fighting infection
Identify strengths and weakness of a simulation
Use the internet to research important figures in the history of blood transfusions Identify the scientist, his significant contribution to blood transfusions, and the dates on which these contributions were made
Prepare and present an oral presentation of their research to the class by creating a living timeline
Examine the ABO antigens found on red blood cells and the antibodies that are present in the bloodstream Identify the antigens that make each blood type unique
Construct a model of antigens involved in ABO blood group
Identify the cause of agglutination as well as the reason why some blood types are able to be mixed
Define critical attributes of human chromosomes
Match homologous chromosomes to make a human karyotype
Demonstrate how traits are encoded in genes found on our chromosomes
Locate specific genes on human chromosomes
Demonstrate how traits are encoded in genes found on chromosomes
Infer how genes determine the ABO blood types
Predict the blood types of offspring from parents of known blood types using Punnett Squares
Demonstrate how Punnett Squares are related to genes and chromosomes
Create models of chromosome 9, which contains the ABO genes
Investigate the inheritance of the ABO blood type
Predict blood types of offspring
Demonstrate how chromosomes are related to Punnett Squares
Simulate the change in frequency of alleles due to natural selection by using the class to represent a sample population
Examine the worldwide distribution of the ABO blood types
Observe patterns among the locations where these blood types are prevalent
Locate geographic locations on a world map
Devise a color key to mark the location of the ABO blood types
Activity 3C - Part 4: Born of Blood: Inheritance of Blood Types Pre/Post Test
Activity 3C - Part 4: Born of Blood: Inheritance of Blood Types Pre/Post Test Answer Sheet & Key
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M.O.R.E. Curriculum Program Funding 2003-2008:
National Institutes of Health
National Heart, Lung, and Blood Institute
Minority K-12 Initiative for Teachers and Students
Grant # R25 HL75777
