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- Focus: Students will examine and identify antigens, antibodies, and blood types, and also infer how genes and chromosomes determine blood types.
Activities | Objectives | Resources & Web Sites
Activities
Activity 3A: Hey, What's Your Type? |
(blood, abo blood group, blood group, antigen, red blood cell, blood type)
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| Activity 3B: Why Opposites Attract - Agglutination |
(blood, abo blood group, blood group, antigen, red blood cell, blood type, antibody, antibodies, agglutination)
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| Activity 3C - Part 1: Born of Blood: Craft Stick Chromosomes |
(chromosome, karyotype, trait, gene)
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| Activity 3C - Part 2: Born of Blood: Chromosome Chronicles |
(chromosome, gene, genome, nucleus)
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| Activity 3C - Part 3: Born of Blood: Fun Punns |
(chromosome, gene, blood type, punnett square, inherit)
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| Activity 3C - Part 4: Born of Blood: Inheritance of Blood Types |
(chromosome, gene, blood type, punnett square, inherit)
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| Activity 3D: Pre Hardy Weinberg |
(antigen, blood group, allele, Punnett square, homozygous, heterozygous)
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| Activity 3E: Where in the World is Your Blood Type? |
(world map, map, ABO blood type, blood type, geography)
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| Activity 3F: B.O.A. Responders: Safe and Unsafe Transfusions |
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| Activity 3G: Blood Bank Robberies: Safety of the Blood Supply |
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| Activity 3H: It's Gotta Match! Organ Donations |
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Objectives
Students will be able to:
- Examine the ABO antigens found on red blood cells and the antibodies that are present in the bloodstream
- Identify the antigens that make each blood type unique
- Construct a model of antigens involved in ABO blood group
- Identify the cause of agglutination as well as the reason why some blood types are able to be mixed
- Define critical attributes of human chromosomes
- Match homologous chromosomes to make a human karyotype
- Demonstrate how traits are encoded in genes found on our chromosomes
- Locate specific genes on human chromosomes
- Demonstrate how traits are encoded in genes found on chromosomes Infer how genes determine the ABO blood types
- Predict the blood types of offspring from parents of known blood types using Punnett Squares
- Demonstrate how Punnett Squares are related to genes and chromosomes
- Create models of chromosome 9, which contains the ABO genes
- Investigate the inheritance of the ABO blood type
- Predict blood types of offspring
- Demonstrate how chromosomes are related to Punnett Squares
- Simulate the change in frequency of alleles due to natural selection by using the class to represent a sample population
- Examine the worldwide distribution of the ABO blood types
- Observe patterns among the locations where these blood types are prevalent
- Locate geographic locations on a world map
- Devise a color key to mark the location of the ABO blood types
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Resources & Web Sites
Blood Book website:
http://bloodbook.com
National Heart Lung and Blood Institute
http://www.nhlbi.nih.gov/
PBS Red Gold Website:
http://www.pbs.org/wnet/redgold/basics/
Online Mendelian Inheritance in Man website:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=omim
The Human Genome Project at Sanger Centre at the Welcome Trust Genome Campus
http://www.wellcome.ac.uk/doc_WTD002945.html
Chromosomes and Genetic Mapping
http://www.woodrow.org/teachers/bi/1994/chromosomes.html
Human Genome Project
http://www.ornl.gov/sci/techresources/Human_Genome/home.shtml
National Center for Biotechnology Information, National Institutes of Health
http://www.ncbi.nlm.nih.gov/
The Human Gene Map, National Center for Biotechnology Information
http://www.ncbi.nlm.nih.gov/SCIENCE96/chr.cgi?9
Genome News Network Website
http://www.genomenewsnetwork.org/
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