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Entire Activity Download (12 pages)
Individual Downloads
Keywords chromosome, karyotype, trait, gene
Search Curricular Keywords
Key Concepts
Karyotype, Chromosome
Mapping, Genes,
and Chromosomes
Process Skills Utilized
Making inferences,
synthesizing information
Intended Grade Level - 6-8
Objectives
Using wooden craft stick chromosomes, students will be able to:
- Define critical attributes of human chromosomes
- Match homologous chromosomes to make a human karyotype
- Demonstrate how traits are encoded in genes found on our chromosomes
Activity Description
Working in groups of eight, students will be given six Craft Stick Chromosomes from a set of 46. Since chromosomes exist in pairs within our cells, someone else in the group has a chromosome that will “match” and create a chromosome pair. Students must define critical attributes of their chromosomes as they look for “matching” chromosomes. When each student finds their six “matches”, they use the Chromosome Key Card to number their chromosome pairs. Students will then create a karyotype of their Craft Stick Chromosomes by arranging them in sequential pairs. Once students understand that chromosomes have identifying characteristics, they are ready to map a few specific genes on a chromosome and create a large, mapped model of a chromosome. When all of the large chromosomes are completed, the classroom will become a giant nucleus with a complete set of 46 chromosomes.
Activity Materials
- 1 copy of Student Information Page per group
- 1 copy of Student Data Page per student
- 1 set of Chromosome Patterns per group
- 24 slim craft sticks in assorted colors per group of 4
- 1 Metric ruler per student
- Scissors
- Colored markers
- Glue Sticks
Activity Management Suggestions
Review group skills with students.
Review basic definitions of genes and chromosomes.
If students use scissors to cut the sticks, they should wear safety goggles and take care that pieces of the craft sticks do not fly across the room, causing injury to themselves or their classmates.
For a change of pace, consider taking students outside as they assemble their Chromosome Model Karyotypes.
References Used
Online Mendelian Inheritance in Man website:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=omim
The Human Genome Project at Sanger Centre at the Welcome Trust Genome Campus
http://www.wellcome.ac.uk/doc_WTD002945.html
Chromosomes and Genetic Mapping
http://www.woodrow.org/teachers/bi/1994/chromosomes.html
Human Genome Project
http://www.ornl.gov/sci/techresources/Human_Genome/home.shtml
National Center for Biotechnology Information, National Institutes of Health
http://www.ncbi.nlm.nih.gov/
The Human Gene Map, National Center for Biotechnology Information
http://www.ncbi.nlm.nih.gov/SCIENCE96/chr.cgi?9
Genome News Network Website
http://www.genomenewsnetwork.org/
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