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Entire Activity Download (24 pages)
Individual Downloads
Keywords chromosome, gene, blood type, punnett square, inherit
Search Curricular Keywords
Key Concepts
Inheritance of
ABO blood types,
Punnett Squares,
Genes,
Chromosomes
Process Skills Utilized
Making Inferences,
synthesizing information
Intended Grade Level - 6-8
Objectives
Using descriptive cards and large Punnett Squares, students will be able to:
- Infer how genes determine the ABO blood types
- Predict the blood types of offspring from parents of known blood types using Punnett Squares
- Demonstrate how Punnett Squares are related to genes and chromosomes
Activity Description
Using giant Punnett Squares, crepe paper chromosome streamers and descriptive cards, students will work in groups of eight to explore the inheritance of ABO blood types. They will also predict the ABO blood types of offspring from various genetic crosses. Students will assume the roles of Random Runner, Chromo-Caller, Likli' Hoods (possible offspring), Mom G'nome and Dad G'nome as they explore the world of Punnett Squares in a kinesthetic, fun way.
Activity Materials (per group of 8)
- 1 copy of Student Information Page
- 1 copy of Student Data Page per student
- 1 roll red crepe paper streamer (A gene)
- 1 roll blue crepe paper streamer (B gene)
- 1 roll yellow crepe paper streamer (O gene)
- 1 roll masking tape (colored if possible)
- 1 set task cards (laminated for reuse if possible)
- 1 set of Role Signs with string attached (laminated for reuse if possible)
- 1 set of Chromo Cross Cards (laminated if possible)
- Meter stick
- Scissors
- 4 pair disposable gloves: one from each pair labeled From Mom and one from each pair labeled From Dad
- 1 Marker
Activity Management Suggestions
1. If possible, laminate the Role Cards and Role Signs so they can be reused.
2. Using masking tape, preferably colored, mark off three or four six-foot Punnett Squares on the floor and number each square.
3. Divide the class into groups of 8 and review group role assignments and expected behavior. Assign each group to one of the giant Punnett Squares.
4. Cut 8 one-meter strips of crepe paper in each color per group. Each group will have 24 crepe paper chromosome strips when they finish.
5. Using a maker, make a mark 30 cm from one end of the crepe paper chromosome. Label it ABO gene.
6. If the crepe paper chromosome streamer is red, label the gene A. If the streamer is blue, label the gene B and if the streamer is yellow, label the gene O.
7. Have each student choose a Role Card and matching Role Sign with string attached so they can hang the sign around their necks. Instruct students to read the Role Card and be sure they understand their job as described on the card.
References Used
The Human Genome Project at Sanger Centre at the Welcome Trust Genome Campus
http://www.wellcome.ac.uk/doc_WTD002945.html
Chromosomes and Genetic Mapping
http://www.woodrow.org/teachers/bi/1994/chromosomes.html
Human Genome Project
http://www.ornl.gov/sci/techresources/Human_Genome/home.shtml
National Institutes of Health
National Center for Biotechnology Information,
National Institutes of Health, Bethesda MD 20894, USA.
http://www.ncbi.nlm.nih.gov/SCIENCE96/chr.cgi?9
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