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Entire Activity Download (21 pages)
Individual Downloads
Assessment
Keywords chromosome, gene, blood type, punnett square, inherit
Search Curricular Keywords
Key Concepts
Blood types,
punnett squares,
genes,
chromosomes
Process Skills Utilized
Predicting,
observing,
inferring,
drawing conclusions
Intended Grade Level - 6-8
Objectives
Using curling ribbon models to simulate chromosomes, students will be able to:
- Create models of chromosome 9, which contains the ABO genes
- Investigate the inheritance of the ABO blood type
- Predict blood types of offspring
- Demonstrate how chromosomes are related to Punnett Squares
Activity Description
Students will create models of chromosome 9, which contains the ABO blood type genes. Using the chromosome models, they will create gene combinations for each of the 4 blood types. Finally, again using the chromosome models and a graphic organizer, students will simulate blood type inheritance and predict blood types that are possible from genetic crosses.
Activity Materials (per group)
- 1 copy Student Information Page
- 1 copy Student Data Page per student
- 80 cm blue curling ribbon*
- 80 cm yellow curling ribbon*
- 80 cm red curling ribbon*
- Permanent marker
- Ruler
- Scissors
- (24) 3/8” diameter Velcro dots (Alternately cut six small pieces off of Velcro tape)
- Yellow, Blue and Red map pencils
*Note: Any three colors of curling ribbon can be used
Activity Management Suggestions
Make a transparency of the Punnett Square Template (Student Data Pages) so you can demonstrate how to use it on the overhead. Make laminated class sets of the Punnett Square Template and allow students to write on them with erasable transparency markers.
EXTENSIONS:
- Research other genes found on chromosome 9 using data from the Human Genome. What diseases/conditions are related to chromosome 9?
- Students can research a very rare situation in which two AB parents to have a child with blood type O; due to the “cis-AB” gene.
- Students can research a very rare Bombay blood phenotype
References Used
http://www.wellcome.ac.uk/doc_WTD002945. html
Chromosomes and Genetic Mapping
http://www.woodrow.org/teachers/bi/1994/chromosomes.html
Human Genome Project
http://www.ornl.gov/sci/techresources/Human_Genome/home.shtml
The National Center for Biotechnology Information,
National Institutes of Health, Bethesda MD 20894, USA.
http://www.ncbi.nlm.nih.gov/SCIENCE96/chr.cgi?9
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